Hiring partnerBybit is hiring for 65 rolesAbu Dhabi, AE, Remote · Istanbul, TR +9 See all roles

Python Crypto Jobs

Python is the go-to language for blockchain data science, quantitative trading, backend services, and AI integration in the crypto industry. While Solidity and Rust dominate on-chain development, Python powers the off-chain infrastructure that makes crypto products work: from trading bots and portfolio analytics to on-chain data indexing, machine learning pipelines, and automated testing frameworks.

Salaries for Python developers in crypto range from $110,000 to $220,000, with quantitative developers and ML engineers at crypto trading firms and hedge funds earning substantially more through performance-based compensation. Employers look for proficiency in Python's data ecosystem (pandas, NumPy, scikit-learn), web frameworks (FastAPI, Django), and blockchain-specific libraries like web3.py, along with strong SQL skills and experience with data pipeline tools.

The Python crypto job market in 2026 is broad and growing. The explosion of AI-blockchain projects has dramatically increased demand for Python engineers who can build ML models on on-chain data. Meanwhile, the maturation of DeFi has created opportunities for Python developers in risk modeling, regulatory reporting, and institutional trading infrastructure. Python's versatility ensures it remains central to the crypto technology stack.

162open jobs
$98k–150ktypical salary
78companies hiring
27added this week
70%remote

Open Python roles

29 jobs
Remote Salary shown

Senior Software Engineer, Aggregation & Search

New
Chainalysis · Remote
PostgreSQLJava SpringKafkaAWS
today View →

Associate/VP, Back-End Software Engineer

New
Galaxy · Remote · IN
JavaPythonSpring BootFastAPI
today View →

Blockchain Risk Control Lead

New
Bybit · Remote
LLM techniquesblockchain securitydata analysismachine learning
1 day ago View →

SOC Analyst

New
Consensys · Remote
AWSPythonGoBash
1 day ago View →

Senior Infrastructure Engineer, Government Systems

Chainalysis · Remote
KubernetesTerraformLinuxCI/CD
$150k–200k 3 days ago View →

Director, Data Architecture (AI Enablement)

Digital Asset · New York, US
GCPSnowflakeDatabricksBigQuery
$225k–260k 3 days ago View →

Engineering Manager, Web Automation & Open Banking Infrastructure

Zero Hash · Remote · US
TypeScriptJavaScriptGolangNode.js
5 days ago View →

QA Engineer - Zero Hash

Zero Hash · Remote · Chicago, US
QAAPI testingAutomation testingTest case design
5 days ago View →

Core Architect & Integration Lead, Applied AI

Zero Hash · Remote · New York, US
Pythonevent-driven systemsAPI integrationCI/CD
5 days ago View →

Off-Cycle Fall 2026 Cybersecurity Internship

Galaxy · Remote
PythonRustC++Solidity
$55 6 days ago View →

Blockchain Analyst (OSINT / Investigations) and Senior Security Engineer

Inca Digital and Parity · Remote
PythonSQLRustML frameworks
$2k–4k 7 days ago View →

Senior DevOps Engineer (Blockchain)

Omega Solutions · Santa Clara, CA
LinuxKubernetesDockerCI/CD
$3k 7 days ago View →

Blockchain Analyst (OSINT / Investigations)

Inca Digital · Remote
OSINTPythonSQLdata analysis
$2k–4k 9 days ago View →

Senior Settlement & Trading Operations Engineer

Zero Hash · Remote
SQLPythonAI toolingAPI integration
10 days ago View →

Technical Support Engineer - Zero Hash

Zero Hash · Remote · Chicago, US
Technical TroubleshootingREST APIsSQLPython
10 days ago View →

Bitcoin Security Engineer - Strategy

Strategy · Tysons Corner, US
penetration testingcryptographyinformation securityblockchain
$104k–187k 10 days ago View →

Staff Data Scientist

Chainalysis · Remote
PythonSQLmachine learningstatistics
11 days ago View →

Senior DevOps Engineer

FP Markets · Remote
AWSTerraformAnsibleL2/L3 concepts
12 days ago View →

Frontend Software Engineer / Data Product Lead

Tether / LI.FI · Remote
ReactPreactTypeScriptRedux
$100k–160k 12 days ago View →

Staff Machine Learning Engineer

Phantom · Remote
PythonScalaJavaPyTorch
12 days ago View →

Solutions Architect

Chainalysis · Remote
REST APISQLPythonAI tooling
16 days ago View →

Senior Database Administrator - Core Infrastructure

Kraken · Remote
MariaDBMySQLCI/CDGitOps
17 days ago View →

Senior Data Engineer

Trust Wallet · Remote
PythonSparkDatabricksSQL
18 days ago View →

Quant/ML Researcher

hirix · Remote
PythonMLDLquantitative analysis
20 days ago View →

Software Engineer (DeFi / Intents)

1010.trading · Remote
PythonRust
22 days ago View →

Frequently asked questions

How is Python used in crypto?
Python is widely used for blockchain data analysis, quantitative trading, bot development, backend APIs, machine learning on on-chain data, testing automation, and scripting for DeFi operations. Libraries like web3.py and brownie connect Python to blockchain networks.
What Python crypto jobs pay the most?
Quantitative developers at crypto trading firms earn the highest salaries, often $200K-$400K+ with performance bonuses. ML engineers at AI-blockchain startups and senior data engineers at exchanges also command premium compensation.
What skills should I learn alongside Python for crypto?
SQL for data querying, web3.py for blockchain interaction, pandas for data analysis, and FastAPI for building backend services. Understanding of blockchain fundamentals, DeFi mechanics, and basic Solidity helps you work more effectively with on-chain data.