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Python Crypto Jobs

Python is the go-to language for blockchain data science, quantitative trading, backend services, and AI integration in the crypto industry. While Solidity and Rust dominate on-chain development, Python powers the off-chain infrastructure that makes crypto products work: from trading bots and portfolio analytics to on-chain data indexing, machine learning pipelines, and automated testing frameworks.

Salaries for Python developers in crypto range from $110,000 to $220,000, with quantitative developers and ML engineers at crypto trading firms and hedge funds earning substantially more through performance-based compensation. Employers look for proficiency in Python's data ecosystem (pandas, NumPy, scikit-learn), web frameworks (FastAPI, Django), and blockchain-specific libraries like web3.py, along with strong SQL skills and experience with data pipeline tools.

The Python crypto job market in 2026 is broad and growing. The explosion of AI-blockchain projects has dramatically increased demand for Python engineers who can build ML models on on-chain data. Meanwhile, the maturation of DeFi has created opportunities for Python developers in risk modeling, regulatory reporting, and institutional trading infrastructure. Python's versatility ensures it remains central to the crypto technology stack.

167open jobs
$98k–150ktypical salary
79companies hiring
21added this week
71%remote

Open Python roles

136 jobs
Remote Salary shown

Staff Machine Learning Engineer

Coinbase · Remote - USA
machine learningdeep learningLLMsgraph neural networks
$150k–250k 9 days ago View →

Senior Database Administrator (PostgreSQL)

Btse · Remote · Southeast Asia, Taipei
PostgreSQLAWSSQLTerraform
$90k–150k 9 days ago View →

Web/App Test Engineer

Binance · Remote · Asia, Hong Kong, Taipei, Taiwan
JavaPythonJavaScriptSelenium
$82k–138k 9 days ago View →

Senior Business Intelligence Manager

Bybit · Tel Aviv, IL
SQLPythonTableauPower BI
10 days ago View →

Backend Engineer - Blockaid

Blockaid · New York, United States; Tel Aviv, IL
GORustPythonSQL
10 days ago View →

Security Data Analyst

Blockaid · New York, United States; Tel Aviv, IL
SQLPythondata visualizationTableau
10 days ago View →

Protocol Engineer - Plume

Plume · Remote
Distributed systemsconsensus protocolsstorage/database systemshigh performance systems
11 days ago View →

Full Stack Software Developer

Halborn · Remote · Miami, US
ReactTypeScriptPythonNode.js
11 days ago View →

Linux System Engineer

Bitdeer · San Jose, California, US
LinuxShell scriptingPythonPerl
$130k–195k 11 days ago View →

SRE Monitoring Platform Software Engineer (Entry Level)

Bitdeer · Remote · San Jose, US
GoPythonJavaRust
$105k–155k 12 days ago View →

Lead Data Analyst

Animoca Brands · Remote · China, Hong Kong, Singapore
SQLPythondata analysisAI tools
$90k–150k 12 days ago View →

Senior Security Solutions Engineer

Hypernative · Remote
PythonWeb3 technologiesblockchain securitycybersecurity principles
12 days ago View →

Senior Data Scientist

Nexo · Remote · Sofia, BG
SQLPythonPySpark
12 days ago View →

Business Management Intern

QCP Capital · Remote · Singapore, SG
Microsoft OfficeExcelPowerPointWord
13 days ago View →

Trading Desk Operations, Quant Trading Team

Crypto.com · Remote · Hong Kong, HK
PythonAI tools
14 days ago View →

Applied Data Scientist (Pioneer Talent Program)

Binance · Remote · Asia
PythonMLAILLM
14 days ago View →

Senior Risk Analyst

Coinbase · Remote - USA
SQLPythonTableauLooker
$90k–150k 14 days ago View →

Finance Systems Specialist (12 months contract)

Binance · Remote · Asia, Hong Kong
PythonSQLExcel/VBAlow-code platforms
$105k–175k 14 days ago View →

Finance Systems Specialist (12 months contract)

Binance · Remote
PythonSQLExcelVBA
14 days ago View →

Senior Security Engineer, Product & Infrastructure

Squads · Remote
TypeScriptRustGoPython
15 days ago View →

Senior Risk Analyst

Coinbase · Remote
risk managementdata analysisSQLPython
$167k–197k 15 days ago View →

Senior Pricing Analyst

Figure · Remote
data analyticscapital marketsloan pricingcredit risk
$68k–102k 15 days ago View →

Systematic Trader

Crypto · Tel Aviv, IL
Python ProgrammingSQLQuantitative TradingQuantitative Data Analysis
$38k–62k 15 days ago View →

Trader (Market Making)

B2C2 · Remote · London, GB
PythonSQL
16 days ago View →

Junior Quantitative Researcher

Selini Capital · New York, US
PythonC++machine learningstatistics
16 days ago View →

Frequently asked questions

How is Python used in crypto?
Python is widely used for blockchain data analysis, quantitative trading, bot development, backend APIs, machine learning on on-chain data, testing automation, and scripting for DeFi operations. Libraries like web3.py and brownie connect Python to blockchain networks.
What Python crypto jobs pay the most?
Quantitative developers at crypto trading firms earn the highest salaries, often $200K-$400K+ with performance bonuses. ML engineers at AI-blockchain startups and senior data engineers at exchanges also command premium compensation.
What skills should I learn alongside Python for crypto?
SQL for data querying, web3.py for blockchain interaction, pandas for data analysis, and FastAPI for building backend services. Understanding of blockchain fundamentals, DeFi mechanics, and basic Solidity helps you work more effectively with on-chain data.