Hiring partnerBybit is hiring for 65 rolesAbu Dhabi, AE, Remote · Istanbul, TR +9 See all roles

Python Crypto Jobs

Python is the go-to language for blockchain data science, quantitative trading, backend services, and AI integration in the crypto industry. While Solidity and Rust dominate on-chain development, Python powers the off-chain infrastructure that makes crypto products work: from trading bots and portfolio analytics to on-chain data indexing, machine learning pipelines, and automated testing frameworks.

Salaries for Python developers in crypto range from $110,000 to $220,000, with quantitative developers and ML engineers at crypto trading firms and hedge funds earning substantially more through performance-based compensation. Employers look for proficiency in Python's data ecosystem (pandas, NumPy, scikit-learn), web frameworks (FastAPI, Django), and blockchain-specific libraries like web3.py, along with strong SQL skills and experience with data pipeline tools.

The Python crypto job market in 2026 is broad and growing. The explosion of AI-blockchain projects has dramatically increased demand for Python engineers who can build ML models on on-chain data. Meanwhile, the maturation of DeFi has created opportunities for Python developers in risk modeling, regulatory reporting, and institutional trading infrastructure. Python's versatility ensures it remains central to the crypto technology stack.

163open jobs
$98k–150ktypical salary
79companies hiring
25added this week
70%remote

Open Python roles

163 jobs
Remote Salary shown

Senior Data Engineer

Gemini · New York, United States, Miami, Remote (US)
PythonSQLETL
$126k–180k 1 month ago View →

Staff Application Security Engineer

Gemini · New York, United States, Miami, Remote (US)
PythonAIApplication Security
$168k–240k 1 month ago View →

Member of Client Operations, Settlements

Anchorage Digital · San Francisco, US
SettlementsReconciliationsPython
1 month ago View →

SOC Security Engineer

Binance · Remote (APAC)
PythonAWSSIEM
1 month ago View →

Senior Software Engineer (Java)

Btse · Road Town, Tortola, VG
Javareal-time data systemsmulti-threadingconcurrency
$105k–175k 1 month ago View →

Development Lead

Binance · Remote · Asia
AWSJavaPythonGo
$82k–138k 1 month ago View →

Data Analyst Team Lead

Binance · Remote · Asia
Data AnalyticsData VisualizationSQLPython
$75k–125k 1 month ago View →

Data Scientist Markets

Polymarket · New York City, US
PythonSQLTrading
$200k–300k 1 month ago View →

IT Engineer

Ondo Finance · Remote (US)
IAMSaaSOktaGoogle Workspace
1 month ago View →

Staff Backend Engineer - Mesh

Mesh · Remote · Bangalore, IN
C#C++GoJava
1 month ago View →

AI Platform Engineer, Enablement and Governance Operations

Kraken · Remote
PythonSaaSLLMOAuth
1 month ago View →

Technical Sales Engineer - Digital Asset

Digital Asset · Remote · New York, US
DamlTypescriptPythonJava
$150k–170k 1 month ago View →

Senior Threat Intelligence Engineer

Coinbase · Remote - USA
PythonGoSQL
$105k–175k 1 month ago View →

Senior Onchain Investigator

Coinbase · Remote - USA
PythonGoSQL
$52k–88k 1 month ago View →

Principal Security Architect (On-Chain & Digital Assets)

Btse · Remote
HSMMPCAWSKubernetes
$128k–212k 1 month ago View →

Solutions Architect

Chainalysis · Remote (UK)
REST APISQLPython
1 month ago View →

Staff Platform Security Engineer

Phantom · Remote (NA)
AWSKubernetesTerraformPulumi
$200k–250k 1 month ago View →

Senior Financial Data Engineer

Binance · Remote (APAC)
SQLFlinkJavaScala
1 month ago View →

Quantitative Trading Strategy Algorithm Engineer

Binance · Remote (Hong Kong)
PythonMachine LearningDeep Learning
1 month ago View →

Senior Evaluation Algorithm Engineer

Binance · Remote (Hong Kong)
Python
1 month ago View →

Data / ML / AI Intern

Dialectic · Zug, CH
machine learningstatistical analysisPythonRust
1 month ago View →

Software Engineer, Control Plane

Conduit · Remote (US)
GoPythongRPCprotobuf
1 month ago View →

Quantitative Researcher

Polymarket · New York City, US
quantitative analysisPythonmarket microstructure
$250k–350k 1 month ago View →

Team Lead Engineer - Crypto

Alpaca · Remote - EU - LATAM - NA - APAC
PythonGoLangC/C++NodeJS
$75k–125k 1 month ago View →

Trading Operations Analyst

Flowdesk · Paris, FR
cryptocurrencyliquidityrisk managementPython
$90k–120k 1 month ago View →

Frequently asked questions

How is Python used in crypto?
Python is widely used for blockchain data analysis, quantitative trading, bot development, backend APIs, machine learning on on-chain data, testing automation, and scripting for DeFi operations. Libraries like web3.py and brownie connect Python to blockchain networks.
What Python crypto jobs pay the most?
Quantitative developers at crypto trading firms earn the highest salaries, often $200K-$400K+ with performance bonuses. ML engineers at AI-blockchain startups and senior data engineers at exchanges also command premium compensation.
What skills should I learn alongside Python for crypto?
SQL for data querying, web3.py for blockchain interaction, pandas for data analysis, and FastAPI for building backend services. Understanding of blockchain fundamentals, DeFi mechanics, and basic Solidity helps you work more effectively with on-chain data.